Rebalanced wound equilibrium :
Formation of a lipido-colloid gel due to hydration of the CMC-Na+ particles in the Soft-Adherent TLC layer. Creation of a hydrated lipido-colloid film ensures that a moist environment is maintained in order to allow the key cells involved in the skin repair process (fibroblasts, keratinocytes, macrophages) to exert these activities.
With healing accelerator NOSF (Nano-OligoSaccharide Factor), contribution of properties complementing those of TLC Technology. In contact with wound exudate, this Technology leads to formation of a gel that binds preferentially to damaged areas. Healing accelerator NOSF then interacts with the wound micro-environment, neutralising excess proteases (1).
Increased fibroblast proliferation
The multiplication of dermal fibroblasts due to the effects of Soft-Adherent TLC-NOSF Technology is possible again (2), accompanied by a re-triggering of their Extra-Cellular Matrix (ECM) synthesising activity, making it possible for dermal granulation to resume.
Absorption by the absorbent pad:
Vertical absorption prevents any risks of maceration of the wound margins. The exudate absorption volume is, on average, 50ml/100 cm2, while drainage capacity (absorption +MVTR*) is greater than 200 ml/100cm2/24h.
Gas permeability and non-occlusivity:
The non-woven, semi-permeable backing gives the dressing an extremely high permeability
Soft-adherence to the surrounding skin
UrgoStart® incorporates polymers, which guarantee soft-adherence to the peri-wound skin.
This level of adherence has been designed to ensure hold of the dressing when it is applied and to make it easy to position, without causing skin damage when it is removed.
(1) Effet in vitro d’un nouvel inhibiteur de métalloprotéases, communication orale au Congrès des Plaies et Cicatrisations 2008, Paris
M. Bernard, Société BioAlternatives.
(2) Bernard F.X. et al.
Stimulation of the proliferation of human dermal fibroblasts in vitro by a lipidocolloid dressing.
Journal of Wound Care. 2005.