1. What is the composition of UrgoStart®?
UrgoStart® is a soft-adherent foam dressing with TLC-NOSF technology, an innovation from URGO. It consists of two layers: a highly breathable backing, and an absorbent foam pad coated with a soft-adherent TLC-NOSF layer. The healing accelerator NOSF restores the biochemical balance of the wound by neutralising the action of MMPs and the Soft-Adherent TLC-layer stimulates fibroblast proliferation. The foam and the backing control exudate without maceration.
2. Does UrgoStart® affect the pH of the wound?
UrgoStart® has a neutral pH, therefore it does not affect the wound ph.
3. Can UrgoStart® be used with antiseptics?
After having performed the usual wound care protocol and prior to application of UrgoStart®, it is recommended that the wound be rinsed with sterile saline solution.
4. Can UrgoStart® be used on infected wounds?
In the case of a wound showing signs of bacterial colonisation, it is recommended that the infection be treated first by UrgoCell® Silver, prior to the use of UrgoStart®.
5. Is there any risk of the wound drying out?
No. When in contact with the exudate, the dressing forms a lipido-colloid gel, which creates and maintains the moist environment favourable to the healing process.
6. What are the contraindications of UrgoStart®?
UrgoStart® is contraindicated in the case of cancerous wounds and deep fistula wounds.
7. Is there evidence that UrgoStart® is effective?
In a Randomised Controlled Trial conducted on 117 patients, it was demonstrated that the healing rate was multiplied by 4 versus the comparative MMP inhibitor product, due to the action of TLC-NOSF (Schmutz JL, Meaume S, Fays S et al. Evaluation of the nano-oligosaccharid factor lipido-colloid matrix in the local management of venous leg ulcers : results of a randomised, controlled trial, Int Wound J. 2008 jun,6(2); 172-82)
The UrgoStart® dressing significantly stimulates human fibroblast proliferation, which has been observed and demonstrated with UrgoCell® TLC and TLC dressings (Bernard F.X. et al. Stimulation of the proliferation of human dermal fibroblasts in vitro by a lipidocolloid dressing. Journal of Wound Care. 2005. Clinical study in course).
UrgoStart® is available in a variety of different sizes for cost-effectiveness. It can be cut to shape the dressing to the size of the wound.
9. What role do MMPs play in normal healing?
During the inflammation phase that occurs in the wound healing process, MMPs (Matrix Metallo-Proteinases) help to eliminate fragments of damaged tissue in the extracellular matrix, thereby promoting the reconstruction of a new matrix. In order to protect healthy tissue from excessive MMP activity, MMP inhibitors are synthesised physiologically. In the case of a chronic wound, this balance is disrupted and MMPs have increased activity. The healing accelerator NOSF present in UrgoStart® neutralises the activity of proteases and restores the physiological balance.
10. What is Nano-OligoSaccharide Factor (NOSF) and what is its role?
NOSF, Nano-OligoSaccharide Factor is a healing accelerator, which neutralises certain MMPs in order to restore the biochemical balance in wounds. Restoration of the balance between MMPs and MMP inhibitors re-triggers the healing process.
11. Why is the UrgoStart® range different from other treatments?
The UrgoStart® range contains a unique and innovative active substance, NOSF, a healing accelerator capable of re-triggering the healing process in leg ulcers, pressure ulcers and diabetic foot ulcers and recurring wounds.
12. Does UrgoStart® improve fragile surrounding skin?
Due to its non-occlusive and non-adhesive lipido-colloid matrix, UrgoStart® improves the condition of the peri-wound skin.
13. Can UrgoStart® be used on cavity wounds?
No, the limited conformability of UrgoStart® means that it is not ideal for use in cavity wounds. It is recommended that UrgoStart® Contact be used in these cases (contact layer with TLC-NOSF).
14. Is UrgoStart® easy to handle? Does UrgoStart® stick to gloves?
UrgoStart® has tabs for easy application. The soft-adherent TLC layer of UrgoStart® may sticks to latex surgical gloves. It is therefore recommended to avoid contact with this soft-adherent TLC layer.
15. How often should UrgoStart® dressings be changed?
UrgoStart® dressings can be left in place for up to 7 days, depending on the level of exudate and the clinical condition of the wound.